eHealth Solutions Show Promise for Kidney Transplant Medication Adherence
Global, Wednesday, 14 May 2025.
A review found eHealth interventions likely improve medication adherence in kidney transplant patients, but results vary across studies. More research is needed to confirm effectiveness.
Study Details and Methodology
A comprehensive systematic review and meta-analysis examined 12 studies involving 1,234 kidney transplant recipients to evaluate the effectiveness of eHealth interventions for medication adherence [1]. The research, conducted through November 2024, analyzed randomized controlled trials across seven countries, including the United States, Turkey, Australia, South Korea, Germany, Sweden, and Canada [1]. The investigation focused specifically on immunosuppressant medication adherence, a critical factor in preventing graft rejection and loss [1].
Key Findings and Electronic Monitoring
Significant improvements in adherence were observed when measured through electronic monitoring devices, with a risk ratio of 1.46 (P=.006) and mean difference of 0.37 (P<.001) [1]. However, these findings showed instability during sensitivity analyses [1]. The study employed various measurement methods, including self-reported questionnaires, electronic monitoring devices, and tacrolimus trough levels, to ensure comprehensive evaluation of medication adherence patterns [1].
Implementation Challenges and Future Directions
While eHealth interventions show promise, the heterogeneity in trial designs and intervention characteristics presents challenges in drawing definitive conclusions [1]. The research highlighted the need for methodological refinements and larger-scale studies to validate clinical efficacy [1]. This aligns with broader trends in healthcare technology integration, where telenursing and digital health solutions are increasingly being adopted to improve patient outcomes [2][3].